Pe264 Neurotechnology can quantify Cannabis Psychoactive Effects

Part-1-Science w/ Israel Gasperin, Founder & CEO, Zentrela

We discuss how Neuroscience is objectively measuring the psychoactive effects inside the brain of cannabis consumers, and how that could be used to predict future cannabis products. 

One day you might even get this Neurotechnology Headset to use at home, leading to next level cannabis consumer citizen science! 

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Pe262 A New Cannabinoid System in your Body

Part-1-Science w/ Codi Peterson, Pediatric Pharmacist & CSO at Cannigma.

What is the Endocannabinoidome & how is it different from the ECS (Endocannabinoid System) in your body? 

It turns out the cannabinoids found in cannabis do more than work on the CB1 & CB2 Receptors found in your ECS. We discuss this new system, what we actually know and the massive potential hiding behind the many things we don’t know about the Endocannabinoidome.

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Pe260 Targeted Cannabinoid Therapy for Disease

(Part-1-Science) Emma Chasen joins to discuss targeted therapies using cannabinoids. We cover ailments like inflammation, autoimmune disorders, nausea, pain and what we actually know about the science around minor cannabinoids as Emma works through her Masters degree on Cannabis. 

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Pe254 Get any DNA Code, delivered to your door

Michael Hogan, Ph.D., Co-Founder & CSO of PathogenDx, is working on DNA Microarray Technology for next level cannabis testing. We discuss how the technology works, using DNA as a tool, and how you can get a vial of any custom DNA code sent to your door in a few days.

Their technology has a lot of future potential in multiple different industries. We also discuss how they got FDA Emergency Use Authorization for their DNA Microarray based Covid 19 test.

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Pe253 Democratizing Clinical Trials for Cannabis & Hemp

There’s a huge gap in the cannabis market that is unlike any other industry, plant or drug. There are tens of thousands of cannabis/ hemp products on the shelf, while only a handful are available through the pharmaceutical industry. Yet it is only the few pharmaceutical cannabis products being studied through clinical trials. Dr. Jeff Chen, CEO & Co-Founder of Radicle Science, is on a mission to change that.

LINK: Radicle Science ACES Study Results

LINK: Radicle Science ACES Study FAQ

LINK: Radicle Science & OBX Alliance

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Pe252 What’s Actually Known about Cannabis & Cancer?

Kent Vrana PhD, Pharmacology Department Chair & Professor at the Penn State Neuroscience Institute, has been researching molecular neuropharmacology for over 30 years. In his role as Director of Penn State’s Designated Medical Marijuana Center, he’s developed a keen interest in both the medical potential - and the possible harms - of whole plant cannabis & cannabinoid isolates. We discuss the current knowns & unknowns around how cannabinoids fight cancer, whether or not the science behind CBG will live up to marketing hype, and important pharmaceutical drug interactions to look out for when you’re considering CBD or cannabis for medical needs.

LINK: Cannabinoid Drug-Drug Interactions resources from Penn State Pharmacology

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Pe251 Treating Specific Ailments with Cannabis

We had Dr. Jordan Tishler (last ep. Pe247) back on the podcast to discuss more science than politics this time around. We discuss his private practice in Massachusetts, Inhale MD, and his insights on treating specific ailments with cannabis like cancer, pain, anxiety and insomnia. We also cover the current science on topical and sublingual consumption effectiveness.

Dr. Jordan Tishler is the President of the Association of Cannabinoid Specialists, helping educate physicians on the practice of cannabis medicine.

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Pe250 This is sad… Doctors on Autism & Cannabis Use

Janna Champagne, BSN, RN, had an immune health collapse in 2012. After not liking the recommended pharmaceutical options, she found a cannabis protocol that achieved unheard of results for lupus. When her daughter's autism turned for the worse during puberty, she turned to cannabis again. We discuss how autism is classified as a mental disorder, when there’s clear evidence it’s a biological disorder from Endocannabinoid Deficiency.

LINK: Janna’s article on her daughter’s autism & cannabis use

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Pe249 The Biological Chemistry of Cannabis Genetics

Jordan Zager, PhD, is identifying key genetic markers in cannabis related to pathogens, pest attacks, terpenes and cannabinoid profiles. We discuss a gene they recently discovered for making cannabis resistant to powdery mildew and how the future of plant genetics will impact the cannabis industry.

Jordan is the CEO & Co-Founder of Dewey Scientific.
They are currently hiring analytical chemists (discussed in episode).
Other Dewey Links: Frontiers in Agronomy powdery mildew gene study; Dewey Cannabis Website; Dewey Scientific's LinkedIn and Twitter; Dewey Cannabis' Twitter and Instagram

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Pe248 PTSD & Shutting Down your Default Mode Network

Our guest is Ruth Fisher, PhD. We discuss her recent research paper on medicinal cannabis use for PTSD, how psychedelics might also be used for PTSD, the default mode network in your brain and her writing process for summarizing and researching scientific papers.

Ruth is the Author of The Medical Cannabis Primer and a recurring cannabis science columnist for Cannabis Patient Care Magazine.

You can read Ruth's Cannabis for PTSD Science Review in the 2021 Cannabis Patient Care Magazine Veterans' Issue

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Pe247 Gaps & Politics in Cannabis Treatment for Patients

The cannabis industry was built around medical patients, but as federal legalization looms, will those same patients be forgotten in this new regulatory landscape.

Dr. Jordan Tishler is on the faculty at Harvard Medical School and spent 15 years at the VA as an Emergency Physician. He started InhaleMD when those organizations wouldn’t allow him to discuss cannabis with his patients. He then started the Association of Cannabinoid Specialists to address patient care and lobbying for a proper medical cannabis program when federal legalization happens.

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Pe246 Using Cannabis & Psychedelics in Therapy

Cannabis is quickly becoming a recreational product, however many of those “rec consumers” may be buying for medicinal reasons, like anxiety, depression or PTSD.

Saj Razvi, LPC is a psychotherapist and former clinical researcher in the MAPS Phase 2 trial of MDMA-assisted psychotherapy. We discuss his plant medicine therapy approach for finding and treating the root cause of PTSD like symptoms, often rooted in complex, childhood developmental trauma.

Saj Razvi is the Director of Education at the Psychedelic Somatic Institute (PSI).

PSI 101 Training Video: How the body & autonomic nervous system generate many mental health symptoms.

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Pe245 This Led to the Modern Understanding of our ECS

Greg Gerdeman’s Ph.D. dissertation in Pharmacology from Vanderbilt University was one of the first studies to discover endocannabinoids acting as so-called “retrograde messengers” in the brain, which has become a foundation to modern understanding of the ECS and the effects of cannabis. After multiple roles in the industry, Greg started NASHCX to focus on the future of hemp markets.

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Pe243 New Psychedelics for Treating Mental Illness

Psychedelics & Cannabinoids are going mainstream while synthetic designer drugs still flood the market as federal legality lacks to catch up. Dr. Samuel Banister’s (CSO at Psylo) research work has spanned all of these categories. We discuss his past cannabis research, work on synthetic designer drugs and his new venture into psychedelic inspired medicine to treat mental illness.

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Pe242 The Spelman Report on Cannabis

Kevin Spelman, PhD, has decades of experience in nutraceuticals, phytonutrients and cannabinoids while filling CSO and VP of R&D roles in laboratory and clinical research. We discuss the unknown parts of the cannabis plant, targeting specific ailments and combining other plant medicines with cannabis for next level product formulations.

Check out The Spelman Report, a subscription audio journal.

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